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      Plasmid Pain Points In The Gene Therapy Pipeline

      May 10, 2022 4:01:18 PM / by Biotage posted in mRNA, Plasmid, Plasmid Purification, PhyPrep, DNA, Adeno-Associated Virus, Gene Therapy

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      Gene therapy has had its share of setbacks, but finally gene therapies are proving successful at treating diseases like neuromuscular disorders, cancer and blindness. Adeno-associated virus (AAV) has emerged as a leading gene delivery vehicle because it is efficient and has demonstrated safety in humans.

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      Transfection Efficiency: What Makes Plasmid DNA Transfection Grade

      Apr 28, 2022 2:30:00 PM / by Megan Gallagher posted in Maxiprep, Megaprep, Gigaprep, Plasmid, Plasmid Purification, transfection, transient transfection, transfection grade plasmid DNA, Endotoxin, DNA, Supercoiled, Circular DNA, Transfection-grade

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      Successful transient transfection relies on many factors, starting with a successful plasmid prep. To ensure high transfection efficiency, resulting DNA from your plasmid preps must be transfection grade. But what does transfection grade really mean?

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