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      How To Select a Pore Size for C18 Reversed Phase Chromatography

      Mar 23, 2022 12:00:00 PM / by Caleb Ferguson posted in Reversed-phase, mass spec, protein purification, pore size, C18, C18 (300 Å), chromatography


      Reversed-phase chromatography is an essential step in any drug discovery workflow, particularly as a desalting step prior to MS/MALDI analysis. One of the first choices you must make when you design your purification protocol is resin selection, and there are several options to choose from depending on your sample type and downstream application. One important variable to consider among different resin types is pore size.

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